The Natural History Building is located on the University of Georgia campus at the corner of East Campus Drive and Cedar Street. This building houses the administrative and educational offices of the museum, as well as the Arthropods, Herpetology, Ichthyology, Invertebrate, Mammalogy, Ornithology, and Zooarchaeology Collections. Visitors may park in the parking lot adjacent to the building. They should request a visitor's parking permit from the Museum office.

The Botany Herbarium is located in the Miller Plant Sciences Building on the University of Georgia campus at the corner of Brooks Drive and Carlton Street.

The Archaeology Collection is located in the Riverbend Research Lab on Riverbend Road.